Necroptosis in Immuno-Oncology and Cancer Immunotherapy

Immune-checkpoint blockers (ICBs) have revolutionized oncology and firmly established the subfield of immuno-oncology. Despite this renaissance, a subset of cancer patients remain unresponsive to ICBs due to widespread immuno-resistance. To “break” cancer cell-driven immuno-resistance, researchers h...

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Main Authors: Jenny Sprooten, Pieter De Wijngaert, Isaure Vanmeerbeerk, Shaun Martin, Peter Vangheluwe, Susan Schlenner, Dmitri V. Krysko, Jan B. Parys, Geert Bultynck, Peter Vandenabeele, Abhishek D. Garg
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2020-08-01
Serija:Cells
Teme:
cytokines
interferons
danger signals
damage-associated molecular patterns (DAMPs)
dendritic cells
macrophages
Online dostop:https://www.mdpi.com/2073-4409/9/8/1823
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