Interstitial Perfusion Culture with Specific Soluble Factors Inhibits Type I Collagen Production from Human Osteoarthritic Chondrocytes in Clinical-Grade Collagen Sponges.

Articular cartilage has poor healing ability and cartilage injuries often evolve to osteoarthritis. Cell-based strategies aiming to engineer cartilaginous tissue through the combination of biocompatible scaffolds and articular chondrocytes represent an alternative to standard surgical techniques. In...

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Bibliographic Details
Main Authors: Nathalie Mayer, Silvia Lopa, Giuseppe Talò, Arianna B Lovati, Marielle Pasdeloup, Stefania A Riboldi, Matteo Moretti, Frédéric Mallein-Gerin
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5008682?pdf=render
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