ER-α36, a novel variant of ER-α, mediates estrogen-stimulated proliferation of endometrial carcinoma cells via the PKCδ/ERK pathway.

Recently, a variant of ER-α, ER-α36 was identified and cloned. ER-α36 lacks intrinsic transcription activity and mainly mediates non-genomic estrogen signaling. The purpose of this study was to investigate the function and the underlying mechanisms of ER-α36 in growth regulation of endometrial Ishik...

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Hlavní autoři: Jing-Shan Tong, Qing-Hua Zhang, Zhen-Bo Wang, Sen Li, Cai-Rong Yang, Xue-Qi Fu, Yi Hou, Zhao-Yi Wang, Jun Sheng, Qing-Yuan Sun
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2010-11-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC2973969?pdf=render
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