Genome-wide identification of binding sites defines distinct functions for Caenorhabditis elegans PHA-4/FOXA in development and environmental response.

Transcription factors are key components of regulatory networks that control development, as well as the response to environmental stimuli. We have established an experimental pipeline in Caenorhabditis elegans that permits global identification of the binding sites for transcription factors using c...

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Autori principali: Mei Zhong, Wei Niu, Zhi John Lu, Mihail Sarov, John I Murray, Judith Janette, Debasish Raha, Karyn L Sheaffer, Hugo Y K Lam, Elicia Preston, Cindie Slightham, LaDeana W Hillier, Trisha Brock, Ashish Agarwal, Raymond Auerbach, Anthony A Hyman, Mark Gerstein, Susan E Mango, Stuart K Kim, Robert H Waterston, Valerie Reinke, Michael Snyder
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2010-02-01
Serie:PLoS Genetics
Accesso online:http://europepmc.org/articles/PMC2824807?pdf=render
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