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Molecular Lesions of Insulator CTCF and Its Paralogue CTCFL (BORIS) in Cancer: An Analysis from Published Genomic Studies
CTCF (CCCTC-binding factor) is a transcription regulator with hundreds of binding sites in the human genome. It has a main function as an insulator protein, defining together with cohesins the boundaries of areas of the genome called topologically associating domains (TADs). TADs contain regulatory...
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Format: | Artigo |
Sprog: | Inglês |
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MDPI AG
2018-10-01
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Serier: | High-Throughput |
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Online adgang: | http://www.mdpi.com/2571-5135/7/4/30 |
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