General molecular and cellular mechanisms for renal and cardiac remodeling in chronic kidney disease: a target for nephrocardioprotection

The lecture considers a number of molecular and cellular mechanisms underlying the structural and functional rearrangement and development of renal and cardiac fibrosis in chronic kidney disease (CKD). It details the key component of disadaptative organ remodeling (the formation of myofibroblasts vi...

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Autori principali: L V Kozlovskaia, I N Bobkova, M L Nanchikeeva, N V Chebotareva, O A Li, O K Plieva
Natura: Artigo
Lingua:Russo
Pubblicazione: "Consilium Medicum" Publishing house 2013-06-01
Serie:Терапевтический архив
Soggetti:
cardiac fibrosis
nephrofibrosis
epithelial-mesenchymal transdifferentiation
endothelial-mesenchymal transdifferentiation
myofibroblasts
angiotensin ii
plasminogen activator inhibitor
transforming growth factor-β1
vascular endothelial growth factor
cardio- and nephroprotection
vegf
Accesso online:https://ter-arkhiv.ru/0040-3660/article/view/31296
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