Endothelin receptor a blockade is an ineffective treatment for adriamycin nephropathy.

Endothelin is a vasoconstricting peptide that plays a key role in vascular homeostasis, exerting its biologic effects via two receptors, the endothelin receptor A (ETA) and endothelin receptor B (ETB). Activation of ETA and ETB has opposing actions, in which hyperactive ETA is generally vasoconstric...

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Bibliographic Details
Main Authors: Roderick J Tan, Lili Zhou, Dong Zhou, Lin Lin, Youhua Liu
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3825716?pdf=render
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