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Endothelin receptor a blockade is an ineffective treatment for adriamycin nephropathy.
Endothelin is a vasoconstricting peptide that plays a key role in vascular homeostasis, exerting its biologic effects via two receptors, the endothelin receptor A (ETA) and endothelin receptor B (ETB). Activation of ETA and ETB has opposing actions, in which hyperactive ETA is generally vasoconstric...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science (PLoS)
2013-01-01
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| Schriftenreihe: | PLoS ONE |
| Online Zugang: | http://europepmc.org/articles/PMC3825716?pdf=render |
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