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Identification of Novel Covalent XPO1 Inhibitors Based on a Hybrid Virtual Screening Strategy
Nuclear export protein 1 (XPO1), a member of the nuclear export protein-p (Karyopherin-P) superfamily, regulates the transport of “cargo” proteins. To facilitate this important process, which is essential for cellular homeostasis, XPO1 must first recognize and bind the cargo proteins. To inhibit thi...
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| Glavni autori: | , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI AG
2022-04-01
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| Serija: | Molecules |
| Teme: | |
| Online pristup: | https://www.mdpi.com/1420-3049/27/8/2543 |
| Oznake: |
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