Inducing mutations in the mouse genome with the chemical mutagen ethylnitrosourea

When compared to other model organisms whose genome is sequenced, the number of mutations identified in the mouse appears extremely reduced and this situation seriously hampers our understanding of mammalian gene function(s). Another important consequence of this shortage is that a majority of human...

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Bibliographische Detailangaben
Hauptverfasser: S.M.G. Massironi, B.L.F.S. Reis, J.G. Carneiro, L.B.S. Barbosa, C.B. Ariza, G.C. Santos, J.L. Guénet, A.L.B. Godard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Associação Brasileira de Divulgação Científica 2006-09-01
Schriftenreihe:Brazilian Journal of Medical and Biological Research
Schlagworte:
Mouse
Ethylnitrosourea
Mutation
Co-isogenic mutations
Mutagenesis
Online Zugang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000900009
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