PACAP38 in human models of primary headaches

Abstract Background To review the role of PACAP38 in human models of primary headaches, discuss possible mechanisms of PACAP38-induced migraine, and outline future directions. Discussion Experimental studies have established PACAP38 as a potent pharmacological “trigger” molecule of migraine-like att...

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Autori principali: Håkan Ashina, Song Guo, Anne L. H. Vollesen, Messoud Ashina
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2017-11-01
Serie:The Journal of Headache and Pain
Soggetti:
PACAP38
Human provocation models
Primary headaches
PAC1
Migraine
Accesso online:http://link.springer.com/article/10.1186/s10194-017-0821-3
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