Should young children with sickle cell disease and an available human leukocyte antigen identical sibling donor be offered hematopoietic cell transplantation?

Availability of an HLA-identical sibling donor raises the question, “should young children with SCD, and an available HLA identical sibling donor be considered for hematopoietic cell transplantation (HCT) even before they manifest severe clinical presentations of sickle cell disease (SCD)?” The over...

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Bibliographic Details
Main Author: Lakshmanan Krishnamurti
Format: Artigo
Language:Inglês
Published: Elsevier 2020-06-01
Series:Hematology/Oncology and Stem Cell Therapy
Subjects:
Anemia
Sickle cell
Hematopoietic stem cell transplantation
Disease-free survival
Quality of life
Bioethics
Online Access:http://www.sciencedirect.com/science/article/pii/S1658387620300273
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