Assessment of the Angiogenic Potential of 2-Deoxy-D-Ribose Using a Novel in vitro 3D Dynamic Model in Comparison With Established in vitro Assays

Angiogenesis is a highly ordered physiological process regulated by the interaction of endothelial cells with an extensive variety of growth factors, extracellular matrix components and mechanical stimuli. One of the most important challenges in tissue engineering is the rapid neovascularization of...

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Hlavní autoři: Serkan Dikici, Betül Aldemir Dikici, Shirin Issa Bhaloo, Mercedes Balcells, Elazer R. Edelman, Sheila MacNeil, Gwendolen C. Reilly, Colin Sherborne, Frederik Claeyssens
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020-01-01
Edice:Frontiers in Bioengineering and Biotechnology
Témata:
angiogenesis
vascular endothelial growth factor (VEGF)
2-deoxy-D-ribose (2dDR)
thymidine phosphorylase (TP)
angiogenesis assays
shear stress
On-line přístup:https://www.frontiersin.org/article/10.3389/fbioe.2019.00451/full
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