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RIPK1 suppresses apoptosis mediated by TNF and caspase-3 in intervertebral discs

Abstract Background Low back pain has become a serious social and economic burden and the leading cause of disability worldwide. Among a variety of pathophysiological triggers, intervertebral disc (IVD) degeneration plays a primary underlying role in causing such pain. Specifically, multiple indepen...

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Main Authors: Xubin Qiu, Ming Zhuang, Ziwen Lu, Zhiwei Liu, Dong Cheng, Chenlei Zhu, Jinbo Liu
格式: Artigo
語言:Inglês
出版: BMC 2019-04-01
叢編:Journal of Translational Medicine
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在線閱讀:http://link.springer.com/article/10.1186/s12967-019-1886-3
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