Metagenomics-Based, Strain-Level Analysis of Escherichia coli From a Time-Series of Microbiome Samples From a Crohn's Disease Patient

Dysbiosis of the gut microbiome, including elevated abundance of putative leading bacterial triggers such as E. coli in inflammatory bowel disease (IBD) patients, is of great interest. To date, most E. coli studies in IBD patients are focused on clinical isolates, overlooking their relative abundanc...

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Hlavní autoři: Xin Fang, Jonathan M. Monk, Sergey Nurk, Margarita Akseshina, Qiyun Zhu, Christopher Gemmell, Connor Gianetto-Hill, Nelly Leung, Richard Szubin, Jon Sanders, Paul L. Beck, Weizhong Li, William J. Sandborn, Scott D. Gray-Owen, Rob Knight, Emma Allen-Vercoe, Bernhard O. Palsson, Larry Smarr
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018-10-01
Edice:Frontiers in Microbiology
Témata:
inflammatory bowel disease
Escherichia coli
metagenomics
gut microbiome
de novo assembly
On-line přístup:https://www.frontiersin.org/article/10.3389/fmicb.2018.02559/full
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