Synergistic effect of antimetabolic and chemotherapy drugs in triple-negative breast cancer

The triple-negative breast cancer (TNBC) subtype comprises approximately 15% of all breast cancers and is associated with poor long-term outcomes. Classical chemotherapy remains the standard of treatment, with toxicity and resistance being major limitations. TNBC is a high metabolic group, and antim...

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Bibliographic Details
Main Authors: Elena López-Camacho, Lucía Trilla-Fuertes, Angelo Gámez-Pozo, Irene Dapía, Rocío López-Vacas, Andrea Zapater-Moros, María Isabel Lumbreras-Herrera, Pedro Arias, Pilar Zamora, Juan Ángel Fresno Vara, Enrique Espinosa
Format: Artigo
Language:Inglês
Published: Elsevier 2022-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Triple-negative breast cancer
Antimetabolic drugs
Chemotherapy drugs
Synergism
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222002323
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