Isolating Human Monoclonal Antibodies Against Adeno-Associated Virus From Donors With Pre-existing Immunity

With the advent of single B-cell cloning technology, we can isolate antibodies against virtually any antigen to study the interaction of a given pathogen with the immune system and develop novel therapeutic strategies. Antibodies directed against the capsid of adeno-associated viruses (AAV) are a si...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: April R. Giles, Roberto Calcedo, Anna P. Tretiakova, James M. Wilson
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020-07-01
Серии:Frontiers in Immunology
Предметы:
adeno-associated virus
human monoclonal antibody
memory B-cell
single cell cloning
vector engineering
gene therapy
Online-ссылка:https://www.frontiersin.org/article/10.3389/fimmu.2020.01135/full
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы