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Molecular interactions of EphA4, growth hormone receptor, Janus kinase 2, and signal transducer and activator of transcription 5B.

We previously reported that EphA4, a member of the Eph family of receptor tyrosine kinases, is an important modulator of growth hormone (GH) signaling, leading to augmented synthesis of insulin-like growth factor 1 (IGF1) for postnatal body growth. In the present study, we report the molecular inter...

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Main Authors: Takahiro Sawada, Daiki Arai, Xuefeng Jing, Masayasu Miyajima, Stuart J Frank, Kazushige Sakaguchi
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC5501605?pdf=render
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