Shuang-Huang-Lian prevents basophilic granulocyte activation to suppress Th2 immunity

Abstract Background Basophilic granulocytes (BGs) not only initiate the induction of Th2 cell differentiation, but also amplify the ongoing Th2 response. Shuang-Huang-Lian (SHL) is clinically used for relieving type I hypersensitivity by continuous treatment for several weeks. Methods ELISA, flow cy...

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Hauptverfasser: Qiaoling Fei, Yixin Han, Ruijuan Qi, Yuan Gao, Lei Fang, Rui Hou, Runlan Cai, Yun Qi
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2018-01-01
Schriftenreihe:BMC Complementary and Alternative Medicine
Schlagworte:
Basophilic granulocytes (BGs)
Shuang-Huang-Lian (SHL)
Th2 immunity
IL-4
NFAT
Cytosolic Ca2+ (Ca2+[c])
Online Zugang:http://link.springer.com/article/10.1186/s12906-017-2071-y
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