Surfactant-Mediated Airway and Acinar Interactions in a Multi-Scale Model of a Healthy Lung

We present a computational multi-scale model of an adult human lung that combines dynamic surfactant physicochemical interactions and parenchymal tethering between ~16 generations of airways and subtended acini. This model simulates the healthy lung by modeling nonlinear stress distributions from ai...

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Hlavní autoři: Haoran Ma, Hideki Fujioka, David Halpern, Donald P. Gaver
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020-08-01
Edice:Frontiers in Physiology
Témata:
biofluid mechanics
surfactant
multi-scale modeling
fluid–structure interactions
high-performance computing
acute respiratory distress syndrome
On-line přístup:https://www.frontiersin.org/article/10.3389/fphys.2020.00941/full
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