Fabricating Water Dispersible Superparamagnetic Iron Oxide Nanoparticles for Biomedical Applications through Ligand Exchange and Direct Conjugation

Stable superparamagnetic iron oxide nanoparticles (SPIONs), which can be easily dispersed in an aqueous medium and exhibit high magnetic relaxivities, are ideal candidates for biomedical applications including contrast agents for magnetic resonance imaging. We describe a versatile methodology to ren...

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Bibliographic Details
Main Authors: Tina Lam, Pramod K. Avti, Philippe Pouliot, Foued Maafi, Jean-Claude Tardif, Éric Rhéaume, Frédéric Lesage, Ashok Kakkar
Format: Artigo
Language:Inglês
Published: MDPI AG 2016-05-01
Series:Nanomaterials
Subjects:
superparamagnetic iron oxide nanoparticles
nanoparticle ligand functionalization
contrast agents
magnetic resonance imaging
cell internalization
Online Access:http://www.mdpi.com/2079-4991/6/6/100
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