Pronounced Structural and Functional Damage in Early Adult Pediatric-Onset Multiple Sclerosis with No or Minimal Clinical Disability

Pediatric-onset multiple sclerosis (POMS) may represent a model of vulnerability to damage occurring during a period of active maturation of the human brain. Whereas adaptive mechanisms seem to take place in the POMS brain in the short-medium term, natural history studies have shown that these patie...

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Main Authors: Antonio Giorgio, Jian Zhang, Maria Laura Stromillo, Francesca Rossi, Marco Battaglini, Lucia Nichelli, Marzia Mortilla, Emilio Portaccio, Bahia Hakiki, Maria Pia Amato, Nicola De Stefano
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017-11-01
Serier:Frontiers in Neurology
Fag:
multiple sclerosis
MRI
disability
diffusion tensor imaging
resting state networks
connectivity
Online adgang:http://journal.frontiersin.org/article/10.3389/fneur.2017.00608/full
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