Frequency of Factor V Leiden and Prothrombin Polymorphism in South of Iran

Normal hemostasis requires balanced regulation of prothromboticand antithrombotic factors. Inherited alteration of factor Vand prothrombin gene, the G20210A mutation, increases the resistanceof factor V to degradation and booster production ofprothrombin respectively. These alterations can increase...

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Bibliographic Details
Main Authors: Javad Dehbozorgian, Abdolreza Afrasiabi, Majid Yavarian, Golam Reza Panahandeh Shahraki, Mehran Karimi, Mohammadreza Bordbar, Pier M. Mannucci
Format: Artigo
Language:Inglês
Published: Shiraz University of Medical Sciences 2009-06-01
Series:Iranian Journal of Medical Sciences
Subjects:
Factor V Leiden
thrombosis
mutation
prothrombin
Online Access:http://ijms.sums.ac.ir/files/PDFfiles/34_2_09-Dr_%20Karimi.pdf
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