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Early administration of interleukin-6 inhibitors for patients with severe COVID-19 disease is associated with decreased intubation, reduced mortality, and increased discharge

Objective: The aim of this observational study was to determine the optimal timing of interleukin-6 receptor inhibitor (IL6ri) administration for coronavirus disease 2019 (COVID-19). Methods: Patients with COVID-19 were given an IL6ri (sarilumab or tocilizumab) based on iteratively reviewed guidelin...

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Bibliografische gegevens
Hoofdauteurs: Pranay Sinha, Anahita Mostaghim, Catherine G. Bielick, Angela McLaughlin, Davidson H. Hamer, Lee M. Wetzler, Nahid Bhadelia, Maura A. Fagan, Benjamin P. Linas, Sabrina A. Assoumou, Michael H. Ieong, Nina H. Lin, Ellen R. Cooper, Karrine D. Brade, Laura F. White, Tamar F. Barlam, Manish Sagar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020-10-01
Reeks:International Journal of Infectious Diseases
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Online toegang:http://www.sciencedirect.com/science/article/pii/S1201971220305683
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