A 2-Gene Signature Related to Interferon-Gamma Predicts Prognosis and Responsiveness to Immune Checkpoint Blockade of Glioma

BackgroundGliomas represent the most common and aggressive brain malignancy. Interferon-gamma (IFNG) is a potent inducer of immune response, developing IFNG-related gene signature may promote the diagnosis and treatment of this disease.MethodsBulk tumor and single-cell mRNA-seq datasets of glioma ra...

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Autori principali: Yongzhe Li, Hang Ji, Xin Gao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-04-01
Serie:Frontiers in Medicine
Soggetti:
glioma
IFNGR1
IFNGR2
prognostic
tumor relapse
immune checkpoint blockade therapy
Accesso online:https://www.frontiersin.org/articles/10.3389/fmed.2022.846847/full
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