NARD: whole-genome reference panel of 1779 Northeast Asians improves imputation accuracy of rare and low-frequency variants

Abstract Here, we present the Northeast Asian Reference Database (NARD), including whole-genome sequencing data of 1779 individuals from Korea, Mongolia, Japan, China, and Hong Kong. NARD provides the genetic diversity of Korean (n = 850) and Mongolian (n = 384) ancestries that were not present in t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Seong-Keun Yoo, Chang-Uk Kim, Hie Lim Kim, Sungjae Kim, Jong-Yeon Shin, Namcheol Kim, Joshua Sung Woo Yang, Kwok-Wai Lo, Belong Cho, Fumihiko Matsuda, Stephan C. Schuster, Changhoon Kim, Jong-Il Kim, Jeong-Sun Seo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2019-10-01
Cyfres:Genome Medicine
Pynciau:
Whole-genome sequencing
Reference panel
Genotype imputation
Northeast Asians
East Asians
Mynediad Ar-lein:http://link.springer.com/article/10.1186/s13073-019-0677-z
Tagiau: Ychwanegu Tag
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