Baicalein mediates the anti-tumor activity in Osteosarcoma through lncRNA-NEF driven Wnt/β-catenin signaling regulatory axis

Background: Osteosarcoma (OS) is a common type of malignant bone tumor in adolescents with high risk of metastasis. However, the clinical management still remains unsatisfactory. Traditional Chinese medicine (TCM) has been widely considered as an alternative treatment, and their extracts have proved...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Feng-wei Zhang, Li-yang Peng, Chuan-Jian Shi, Jian-chi Li, Feng-xiang Pang, Wei-ming Fu, Xiao-hua Pan, Jin-fang Zhang
Format: Artigo
Langue:Inglês
Publié: Elsevier 2022-03-01
Collection:Journal of Orthopaedic Translation
Sujets:
Osteosarcoma
Baicalein
Wnt/β-catenin signaling
lncRNA-Neighboring Enhancer of FOXA2(lncRNA-NEF)
Metastasis
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2214031X21001042
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