Determination of lipophilicity of some new 1,2,4-triazole derivatives by RP-HPLC and RP-TLC and calculated methods

Experimental and computational approaches were used to estimate the lipophilicity of novel 1,2,4-triazole derivatives. These derivatives have been subjected to this research, because they exhibit antimicrobial activity. The chromatographic analysis of RP-HPLC and RP-TLC was carried out using methano...

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Main Authors: Anna M. Hawrył, Ryszard S. Świeboda, Mateusz S. Gawroński, Magdalena A. Wójciak-Kosior, Łukasz P. Popiołek, Ryszard B. Kocjan
Formato: Artigo
Idioma:Inglês
Publicado: Growing Science 2015-06-01
Series:Current Chemistry Letters
Assuntos:
lipophilicity
1
2
4-triazole derivatives Computed logP
RP-HPLC
RP-TLC
PCA
Acceso en liña:http://www.growingscience.com/ccl/Vol4/ccl_2015_9.pdf
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