Influence of the Protective Antigen, Produced by <i>Bacillus anthracis</i> Asporogenic Recombinant Strain, on the Immune System of Laboratory Animals

Assessment of immunogenicity and biological safety of protective antigen preparation obtained from asporogenic recombinant producer, B. anthracis 55ΔTPA-1(Spo-), is made on the mice (BALB/c species) and Guiney pigs models. It is shown that the development of adaptive immunity in the inoculated with...

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Autori principali: P. Yu. Popova, N. I. Mikshis, O. M. Kudryavtseva, A. Yu. Goncharova, L. V. Novikova, T. N. Kashtanova, Yu. A. Popov, E. A. Smol'kova, A. L. Kravtsov, T. N. Shchukovskaya
Natura: Artigo
Lingua:Russo
Pubblicazione: Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2012-02-01
Serie:Проблемы особо опасных инфекций
Soggetti:
anthrax
protective antigen
immunity
antibodies
Accesso online:https://journal.microbe.ru/jour/article/view/777
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