Omics Analysis Reveals the Mechanism of Enhanced Recombinant Protein Production Under Simulated Microgravity

Simulated microgravity (SMG) is regarded as a suitable environment to produce recombinant proteins. This study showed that β-glucuronidase expressing Escherichia coli had higher productivity of recombinant protein and higher plasmid copy number under SMG compared with the normal gravity condition. T...

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Bibliographic Details
Main Authors: Jie Huangfu, Hye Su Kim, Ke Xu, Xiaoyu Ning, Lei Qin, Jun Li, Chun Li
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
simulated microgravity
omics
recombinant protein
ribosome protein assembly
protein folding
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00030/full
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