Melanoma Inhibitory Activity (MIA) Is Able to Induce Vitiligo-Like Depigmentation in an in vivo Mouse Model by Direct Injection in the Tail

In the complex pathogenesis of vitiligo, the exact mechanism of the dermatosis is still to be clarified. We previously demonstrated that a protein called melanoma inhibitory activity (MIA) is present in non-segmental vitiligo skin and seems to cause the detachment of melanocytes, consequently creati...

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Auteurs principaux: Matteo Bordignon, Roberto Luisetto, Maria Luisa Valente, Marny Fedrigo, Chiara Castellani, Annalisa Angelini, Mauro Alaibac
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020-08-01
Collection:Frontiers in Medicine
Sujets:
melanoma inhibitory activity
skin
vitiligo
melanocyte
autoimmunity
pathogenesis
Accès en ligne:https://www.frontiersin.org/article/10.3389/fmed.2020.00430/full
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