Melanoma Inhibitory Activity (MIA) Is Able to Induce Vitiligo-Like Depigmentation in an in vivo Mouse Model by Direct Injection in the Tail

In the complex pathogenesis of vitiligo, the exact mechanism of the dermatosis is still to be clarified. We previously demonstrated that a protein called melanoma inhibitory activity (MIA) is present in non-segmental vitiligo skin and seems to cause the detachment of melanocytes, consequently creati...

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Bibliographic Details
Main Authors: Matteo Bordignon, Roberto Luisetto, Maria Luisa Valente, Marny Fedrigo, Chiara Castellani, Annalisa Angelini, Mauro Alaibac
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Medicine
Subjects:
melanoma inhibitory activity
skin
vitiligo
melanocyte
autoimmunity
pathogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00430/full
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