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DNA damage response and Autophagy: a meaningful partnership

Autophagy and the DNA damage response (DDR) are biological processes essential for cellular and organismal homeostasis. Herein we summarize and discuss emerging evidence linking DDR to autophagy. We highlight published data suggesting that autophagy is activated by DNA damage and is required for s...

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Main Authors: ARISTIDES G ELIOPOULOS, Sophia Havaki, Vassilis G Gorgoulis
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2016-11-01
Sraith:Frontiers in Genetics
Ábhair:
Rochtain Ar Líne:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00204/full
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