DNA damage response and Autophagy: a meaningful partnership

Autophagy and the DNA damage response (DDR) are biological processes essential for cellular and organismal homeostasis. Herein we summarize and discuss emerging evidence linking DDR to autophagy. We highlight published data suggesting that autophagy is activated by DNA damage and is required for s...

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Autores principales: ARISTIDES G ELIOPOULOS, Sophia Havaki, Vassilis G Gorgoulis
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016-11-01
Colección:Frontiers in Genetics
Materias:
Autophagy
Cell Death
DNA Damage
Inflammation
evolution
senescence
Acceso en línea:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00204/full
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