In Vitro Assessment of the Interaction Potential of Ocimum basilicum (L.) Extracts on CYP2B6, 3A4, and Rifampicin Metabolism

Ocimum basilicum L. or basilicum is a common culinary herb, used as a traditional medicine for various medical conditions including HIV/AIDS and tuberculosis, in Africa. The objective of this study was to evaluate the effect of methanol, ethanol, aqueous and ethyl acetate extracts of the dried leave...

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Main Authors: Saneesh Kumar, Patrick J. Bouic, Bernd Rosenkranz
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2020-04-01
סדרה:Frontiers in Pharmacology
נושאים:
herb-drug interactions
LC-MS
basil
phytoconstituents
CYP450
time-dependent inhibition
גישה מקוונת:https://www.frontiersin.org/article/10.3389/fphar.2020.00517/full
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