A fusion-inhibiting peptide against Rift Valley fever virus inhibits multiple, diverse viruses.

For enveloped viruses, fusion of the viral envelope with a cellular membrane is critical for a productive infection to occur. This fusion process is mediated by at least three classes of fusion proteins (Class I, II, and III) based on the protein sequence and structure. For Rift Valley fever virus (...

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Autores principales: Jeffrey W Koehler, Jeffrey M Smith, Daniel R Ripoll, Kristin W Spik, Shannon L Taylor, Catherine V Badger, Rebecca J Grant, Monica M Ogg, Anders Wallqvist, Mary C Guttieri, Robert F Garry, Connie S Schmaljohn
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Colección:PLoS Neglected Tropical Diseases
Acceso en línea:http://europepmc.org/articles/PMC3772029?pdf=render
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