In vivo activity of miR-34a mimics delivered by stable nucleic acid lipid particles (SNALPs) against multiple myeloma.

Multiple myeloma (MM) is a disease with an adverse outcome and new therapeutic strategies are urgently awaited. A rising body of evidence supports the notion that microRNAs (miRNAs), master regulators of eukaryotic gene expression, may exert anti-MM activity. Here, we evaluated the activity of synth...

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Hlavní autoři: Maria Teresa Di Martino, Virginia Campani, Gabriella Misso, Maria Eugenia Gallo Cantafio, Annamaria Gullà, Umberto Foresta, Pietro Hiram Guzzi, Maria Castellano, Anna Grimaldi, Vincenzo Gigantino, Renato Franco, Sara Lusa, Mario Cannataro, Pierosandro Tagliaferri, Giuseppe De Rosa, Pierfrancesco Tassone, Michele Caraglia
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2014-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC3937395?pdf=render
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