Rats Lacking Dopamine Transporter Display Increased Vulnerability and Aberrant Autonomic Response to Acute Stress

The activity of the hypothalamus–pituitary–adrenal (HPA) axis is pivotal in homeostasis and presides the adaptative response to stress.<b> </b>Dopamine Transporter (DAT) plays a key role in the regulation of the HPA axis. We used young adult female DAT Knockout (KO) rats to assess the ef...

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Autors principals: Placido Illiano, Gregory E. Bigford, Raul R. Gainetdinov, Marta Pardo
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2020-05-01
Col·lecció:Biomolecules
Matèries:
Dopamine Transporter
Stress
Pituitary Gland
HPA axis
Autonomic response
Post-traumatic stress disorder (PTSD)
Accés en línia:https://www.mdpi.com/2218-273X/10/6/842
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