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Ultra-fast evaluation of protein energies directly from sequence.

The structure, function, stability, and many other properties of a protein in a fixed environment are fully specified by its sequence, but in a manner that is difficult to discern. We present a general approach for rapidly mapping sequences directly to their energies on a pre-specified rigid backbon...

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Main Authors: Gevorg Grigoryan, Fei Zhou, Steve R Lustig, Gerbrand Ceder, Dane Morgan, Amy E Keating
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2006-06-01
叢編:PLoS Computational Biology
在線閱讀:http://europepmc.org/articles/PMC1479088?pdf=render
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