Loss of MeCP2 Function Across Several Neuronal Populations Impairs Breathing Response to Acute Hypoxia

Rett Syndrome (RTT) is a neurodevelopmental disorder caused by loss of function of the transcriptional regulator Methyl-CpG-Binding Protein 2 (MeCP2). In addition to the characteristic loss of hand function and spoken language after the first year of life, people with RTT also have a variety of phys...

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Main Authors: Christopher S. Ward, Teng-Wei Huang, Jose A. Herrera, Rodney C. Samaco, Christopher M. McGraw, Diana E. Parra, E. Melissa Arvide, Aya Ito-Ishida, Xiangling Meng, Kerstin Ure, Huda Y. Zoghbi, Jeffrey L. Neul
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neurology
Assuntos:
Rett
MeCP2
hypoxia
sudden death
biomarker
breathing abnormalities
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fneur.2020.593554/full
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