Comprehensive Evaluation and Application of a Novel Method to Isolate Cell-Free DNA Derived From Bile of Biliary Tract Cancer Patients

Cell-free DNA (cfDNA) exists in various types of bodily fluids, including plasma, urine, bile, and others. Bile cfDNA could serve as a promising liquid biopsy for biliary tract cancer (BTC) patients, as bile directly contacts tumors in the biliary tract system. However, there is no commercial kit or...

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Hlavní autoři: Ningjia Shen, Bin Zhu, Wei Zhang, Baoning Nian, Xiaoya Xu, Lianghe Yu, Xiang Ruan, Sheng Chen, Yang Liu, Xinkai Cao, Xintong Shi, Zhikuan Li, Xingfeng Huang, Xiang Wang, Caifu Chen, Lei Xiong, Dadong Zhang, Xiaohui Fu, Yongjie Zhang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-05-01
Edice:Frontiers in Oncology
Témata:
bile
cell-free DNA
extraction
yield
liquid biopsy
On-line přístup:https://www.frontiersin.org/articles/10.3389/fonc.2022.891917/full
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