Genetic diversity of Escherichia coli in gut microbiota of patients with Crohn’s disease discovered using metagenomic and genomic analyses

Abstract Background Crohn’s disease is associated with gut dysbiosis. Independent studies have shown an increase in the abundance of certain bacterial species, particularly Escherichia coli with the adherent-invasive pathotype, in the gut. The role of these species in this disease needs to be elucid...

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Main Authors: Alexander V. Tyakht, Alexander I. Manolov, Alexandra V. Kanygina, Dmitry S. Ischenko, Boris A. Kovarsky, Anna S. Popenko, Alexander V. Pavlenko, Anna V. Elizarova, Daria V. Rakitina, Julia P. Baikova, Valentina G. Ladygina, Elena S. Kostryukova, Irina Y. Karpova, Tatyana A. Semashko, Andrei K. Larin, Tatyana V. Grigoryeva, Mariya N. Sinyagina, Sergei Y. Malanin, Petr L. Shcherbakov, Anastasiya Y. Kharitonova, Igor L. Khalif, Marina V. Shapina, Igor V. Maev, Dmitriy N. Andreev, Elena A. Belousova, Yulia M. Buzunova, Dmitry G. Alexeev, Vadim M. Govorun
格式: Artigo
語言:Inglês
出版: BMC 2018-12-01
叢編:BMC Genomics
主題:
Gut microbiota
Crohn’s disease
Escherichia coli
Gene content
Inflammatory bowel diseases
Metagenomics
在線閱讀:http://link.springer.com/article/10.1186/s12864-018-5306-5
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