Therapeutic Challenges for Cisplatin-Resistant Ovarian Germ Cell Tumors

The majority of patients with advanced ovarian germ cell cancer are treated by cisplatin-based chemotherapy. Despite adequate first-line treatment, nearly one third of patients relapse and almost half develop cisplatin-resistant disease, which is often fatal. The treatment of cisplatin-resistant dis...

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Bibliographic Details
Main Authors: Ugo De Giorgi, Chiara Casadei, Alice Bergamini, Laura Attademo, Gennaro Cormio, Domenica Lorusso, Sandro Pignata, Giorgia Mangili
Format: Artigo
Language:Inglês
Published: MDPI AG 2019-10-01
Series:Cancers
Subjects:
female patients
germ cell tumors
ovarian germ cell tumors
salvage therapy
refractory
high-dose chemotherapy
Online Access:https://www.mdpi.com/2072-6694/11/10/1584
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