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Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650

Background: The epithelial layer of the nasal mucosa is the first barrier for drug permeation during intranasal drug delivery. With increasing interest for intranasal pathways, adequate in vitro models are required. Here, porcine olfactory (OEPC) and respiratory (REPC) primary cells were characteris...

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主要な著者: Simone Ladel, Patrick Schlossbauer, Johannes Flamm, Harald Luksch, Boris Mizaikoff, Katharina Schindowski
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2019-08-01
シリーズ:Pharmaceutics
主題:
オンライン・アクセス:https://www.mdpi.com/1999-4923/11/8/367
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