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Optimization and in-vivo evaluation of isradipine nanoparticles using Box-Behnken design surface response methodology
The isradipine is the potent anti hypertensive drug, which is matrix in polymeric nanoparticle by using solvent evaporation method. In this work, 3-factor, 3-level Box-Behnken design was used to optimize the process parameters like polymer concentration (A), sonication frequency (B) and sonication t...
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Main Authors: | , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
Elsevier
2016-01-01
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叢編: | OpenNano |
主題: | |
在線閱讀: | http://www.sciencedirect.com/science/article/pii/S2352952015300086 |
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