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Genomic analysis reveals a potential role for cell cycle perturbation in HCV-mediated apoptosis of cultured hepatocytes.

The mechanisms of liver injury associated with chronic HCV infection, as well as the individual roles of both viral and host factors, are not clearly defined. However, it is becoming increasingly clear that direct cytopathic effects, in addition to immune-mediated processes, play an important role i...

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Hlavní autoři: Kathie-Anne Walters, Andrew J Syder, Sharon L Lederer, Deborah L Diamond, Bryan Paeper, Charles M Rice, Michael G Katze
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2009-01-01
Edice:PLoS Pathogens
On-line přístup:http://europepmc.org/articles/PMC2613535?pdf=render
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