Arctigenin Enhances the Cytotoxic Effect of Doxorubicin in MDA-MB-231 Breast Cancer Cells

Several reports have described the anti-cancer activity of arctigenin, a lignan extracted from <i>Arctium lappa </i>L. Here, we investigated the effect of arctigenin (ATG) on doxorubicin (DOX)-induced cell death using MDA-MB-231 human breast cancer cells. The results showed that DOX-indu...

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Bibliographic Details
Main Authors: Kyu-Shik Lee, Min-Gu Lee, Yun-Suk Kwon, Kyung-Soo Nam
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
arctigenin
doxorubicin
triple-negative breast cancer
apoptosis-inducing factor
cell death
Online Access:https://www.mdpi.com/1422-0067/21/8/2997
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