ADSCs and adipocytes are the main producers in the autotaxin–lysophosphatidic acid axis of breast cancer and healthy mammary tissue in vitro

Abstract Background Breast cancer is the most common malignancy in women affecting one out of eight females throughout their lives. Autotaxin (ATX) is upregulated in breast cancer which results in increased lysophosphatidic acid (LPA) formation within the tumor. This study’s aim was to identify the...

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Bibliographic Details
Main Authors: Rafael Schmid, Katharina Wolf, Jan W. Robering, Selina Strauß, Pamela L. Strissel, Reiner Strick, Matthias Rübner, Peter A. Fasching, Raymund E. Horch, Andreas E. Kremer, Anja M. Boos, Annika Weigand
Format: Artigo
Language:Inglês
Published: BMC 2018-12-01
Series:BMC Cancer
Subjects:
Breast cancer
Autotaxin
Lysophosphatidic acid
Therapy
ADSC
Online Access:http://link.springer.com/article/10.1186/s12885-018-5166-z
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