Tyrphostin AG17 inhibits adipocyte differentiation in vivo and in vitro

Abstract Background Excessive subcutaneous adiposity in obesity is associated to positive white adipocyte tissue (WAT) differentiation (adipogenesis) and WAT expandability. Here, we hypothesized that supplementation with the insulin inhibitor and mitochondrial uncoupler, Tyrphostin (T-AG17), in vitr...

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Asıl Yazarlar: Alberto Camacho, Juan Carlos Segoviano-Ramírez, Adriana Sánchez-Garcia, Jose de Jesus Herrera-de la Rosa, Jaime García-Juarez, Carlos Alberto Hernandez-Puente, Geovana Calvo-Anguiano, Sergio Rodolfo Maltos-Uro, Alejandra Olguin, Gabriel Gojon-Romanillos, Gabriel Gojon-Zorrilla, Rocio Ortiz-Lopez
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2018-05-01
Seri Bilgileri:Lipids in Health and Disease
Konular:
Tyrphostin
AG17
Adipogenesis
Obesity
Hepatic steatosis
Oxidative phosphorylation
Online Erişim:http://link.springer.com/article/10.1186/s12944-018-0784-7
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