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The Fine LINE: Methylation Drawing the Cancer Landscape
LINE-1 (L1) is the most abundant mammalian transposable element that comprises nearly 20% of the genome, and nearly half of the mammalian genome has stemmed from L1-mediated mobilization. Expression and retrotransposition of L1 are suppressed by complex mechanisms, where the key role belongs to DNA...
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Main Authors: | , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Hindawi Limited
2015-01-01
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Serija: | BioMed Research International |
Online dostop: | http://dx.doi.org/10.1155/2015/131547 |
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